Palmitoylation mechanisms in dopamine transporter regulation
نویسندگان
چکیده
منابع مشابه
Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation.
Palmitoylation is a lipid modification that confers diverse functions to target proteins and is a contributing factor for many neuronal diseases. In this study, we demonstrate using [(3)H]palmitic acid labeling and acyl-biotinyl exchange that native and expressed dopamine transporters (DATs) are palmitoylated, and using the palmitoyl acyltransferase inhibitor 2-bromopalmitate (2BP), we identify...
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ژورنال
عنوان ژورنال: Journal of Chemical Neuroanatomy
سال: 2017
ISSN: 0891-0618
DOI: 10.1016/j.jchemneu.2017.01.002